Advanced Nanoengineering for Glucose Sensing and Drug Delivery Systems

Sakina Saeed, Verrazzano Class of 2024, completed major in Biology

Collaborating in the laboratory with my mentor Dr. Shuiqin Zhou, her doctoral graduate Koushik Bhattacharya, and Dr. Prashun Roy, has been an immensely transformative experience that goes beyond academic pursuits. I had the privilege of being instructed in an Organic Chemistry I lab by Professor Prashun Roy prior to my research experience, and gained a comprehensive understanding of his methodologies and approaches to addressing particular challenges, which set a strong foundation for my subsequent research endeavors.

During our research, our collective efforts were focused on exploring innovative solutions for managing diabetes, specifically investigating the integration of fluorescent systems for glucose sensing and insulin delivery. The primary aspects encountered in this experience on a personal level were growth as an individual, challenges faced, and meaningful insights gained from this research journey.

Embarking on a collaborative research journey with experts in diverse fields such as synthetic chemistry, polymerization techniques, and biomedical applications was truly enlightening. Dr. Zhou’s mentorship not only expanded my technical knowledge but also nurtured critical thinking and problem-solving skills. Working as a team taught me the value of effective communication, collaboration, and leveraging collective expertise to drive meaningful research outcomes. Moreover, this collaborative environment allowed me to build strong professional relationships and learn from the unique perspectives of each team member.

Our research project centered around addressing the challenges faced by individuals with Type 1 diabetes, with a keen focus on the seamless integration of continuous glucose monitoring and precise insulin delivery. Delving into the potential of fluorescent systems for dual functionality not only broadened our horizons but also paved the way for innovative approaches in healthcare. This hands-on experience not only deepened my understanding but also reignited my fervor for contributing to advancements that have a direct and tangible impact on the well-being and quality of life of patients. It was fulfilling to see how our research could potentially transform healthcare practices and improve patient outcomes.

One of the most exhilarating aspects of this research journey was the exposure to advanced machines and tools that revolutionized our approach to scientific inquiry. The Transmission Electron Microscope (TEM), Photoluminescence Spectroscopy (PL), Dynamic Light Scattering (DLS), Nuclear Magnetic Resonance (NMR), and Gel Permeation Chromatography (GPC) were not just instruments in a lab but gateways to a deeper understanding of molecular structures and material properties. The hands-on experience with these technologies not only expanded my technical proficiency but also fostered a deeper appreciation for material characterization techniques and their significance in biomedical applications.

Reflecting on my time in the lab with Dr. Zhou, Koushik, and Dr. Roy, I am grateful for the invaluable experiences, mentorship, and personal growth that this journey has provided. Collaborative research, coupled with exposure to advanced machines and tools, not only expanded my scientific knowledge but also nurtured essential skills such as teamwork, communication, and problem-solving. This experience has deepened my passion for contributing to meaningful research endeavors and has prepared me for future challenges and opportunities in the field of biomedical engineering. While I am passionate about becoming a Physician Assistant (PA) and directly contributing to patient care, this research experience has ignited another found passion for research in a laboratory setting. I envision combining my clinical skills as a PA with continued research in biomedical engineering, aiming to bridge the gap between innovative research and practical healthcare applications. This dual approach will not only enhance my capabilities as a healthcare professional but also contribute significantly to advancing healthcare practices and patient outcomes.