Shadowing Neurosurgery And Researching Liver Regeneration

Joshua Seidman, a Biology major in the Verrazano Class of 2016, had the opportunity to shadow a surgeon and participate in undergraduate research during the summer after his freshman year.  Read below for more details about Joshua's experience.

Joshua (far right) with fellow researchers

My name is Joshua Seidman and I am currently a Verrazano student in the Class of 2016. I am pursuing a BS degree in Biology with hopes of attending medical school after I graduate. It is no surprise that to attend medical school students must do well in school as well as complete internships and research positions.

During the summer of 2013, right before I started my sophomore year, I was blessed with two major opportunities.  The first opportunity was to shadow a surgeon for a week at Penn State Milton S. Hershey Medical Center.  I met the surgeon through one of my father’s coworkers. This was pretty exciting, since it’s not everyday people get a chance to watch neurosurgery.  I arrived not knowing what to expect, yet I was more anxious than ever before. I had been in the operating room many times before, but I never had a chance to see surgery like this.

When it was time for the first surgery, we walked into the operating room and the surgeon started to tell me what was going to happen during the procedure.  He explained to me that when people have a disease such as Parkinson’s Disease or Tourette’s Syndrome, they have uncontrolled muscle spasms that prevent them from doing everyday tasks. He continued to explain that over time the muscle spasms progress and get worse, so medication that worked originally will stop working and leave the patient with few options for treatment. However, this procedure that he was about to do would really help the patient. The procedure was to implant a Deep Brain Stimulator into the patient’s brain in order to decrease the frequency and amplitude of these muscle spasms.

So what is a Deep Brain Stimulator?  It’s a device that disrupts the electrical signals being sent to the brain that are causing these spasms and prevents them from occurring involuntarily. But how do they implant the stimulator? First they scan the patient’s head and get measurements for a mold that can be put onto their head. This mold will then act as a map and map out exactly where the stimulator should be placed. Once the mold is in place it shows the doctors exactly where to make the holes in the skull in order so that they can implant the stimulator.  Once the two holes are drilled, they then attach the stimulator to the mold around the patient’s head and have it slowly implanted. A machine slowly inserts the stimulator while a computer displays the brain waves and amplifies their sounds. Based on comparison to normal brain waves, doctors can then tell when they have reached the correct location for the stimulator. Once it is in place, they remove the mold and they put caps in the holes of the skull in order to close it. Lastly, they create a tunnel under the patient’s skin from the top of their head, down their neck, and to their chest. They then feed the stimulator wires through the tunnel. Once the wires have reached the chest they make a small incision and hook the wires to a small battery that will stay in the patient’s chest. Once the patient is sutured up, they turn on the stimulator and the patient will start to feel relief immediately.  Seeing this procedure was truly fascinating.

During that week, I also viewed a surgery for chronic lower back pain and a brain tumor assessment, but my favorite experience was watching the surgeon remove an abscess in a patient’s brain.   An abscess is a collection of pus due to the inflammatory response to an infection.  In order to remove it the doctor had to drill through the skull and remove the skull cap. Than they slowly had to maneuver around the cranial nerves and major blood vessels in order to get a sample of the pus to determine what kind of bacterial infection they were dealing with. Once they removed a majority of the pus they were able to get a sample and determine that they can get rid of the bacterial infection with antibiotics.  It was incredible!

The second opportunity I had was to participate in research for six weeks at NYU. The lab primarily researched pancreatic cancer and liver regeneration.  I was paired up with a scientist who was researching liver regeneration, so I didn’t really deal with the pancreatic research until the end of my internship.  The purpose of our research was to investigate how the liver regenerates itself and potentially find a way to increase the rate in order to save patients who have severe hepatitis C and/or liver disease.

When I arrived they explained to me that their ongoing research showed that there was a ligand, a substance that forms a complex with a biomolecule to serve a biological purpose, that would potentially increase the rate that the liver can regenerate itself. The specific ligand we were dealing with was called Zymosan.

So how did we test to see if this was a step in right direction? In order to test it, we did what was called a hepatectomy. What this means is that we would surgically remove three of the five lobes of  mice livers. Then before we sutured up the mice, we injected three of the six mice with the ligand. The next step was to wait about 36 hours, and we then removed the rest of their liver and sent it to a company that made us slides.  The information we collected from the slides allowed us to compare the number of cells between the livers of the three mice that didn’t receive the ligand and the three that did.

Towards the end of my research experience, I did work a few days with another scientist who was working on creating a model of pancreatic cancer in mice that resembled pancreatic cancer in humans. This has never been done before, because when humans get pancreatic cancer it causes connective tissue deposits to form which creates a fibrous like tumor. However, in mice they don’t get this fibrous tumor. Every day we injected a number of mice with a certain type of injection that actually created this fibrous tumor. This is the first time anyone has created a perfect model of pancreatic cancer in mice.

There is definitely a lot more to be said about my summer experiences, but I had to pick and choose what I felt was necessary to mention. If anyone has any questions feel free to contact me. I hope this post interested you and I hope it inspired you to go out and make a difference through research or any other outlet that allows you to help change the world one step at a time.

Exploring History: An Undergraduate Research Fellowship Experience

Adriane Musacchio, a student in the Verrazano Class of 2015 who is completing majors in History/Adolescent Education and Dramatic Arts, was awarded an Undergraduate Research Fellowship over the summer.  Read below to learn more about the very interesting work that Adriane has been doing through the fellowship!

Hello!

My name is Adriane Musacchio and I am a Verrazano Honors Student in the Class of 2015. I am currently pursuing a BA in History/Secondary Education and a BS in Dramatic Arts. Last semester I enrolled in Seminar in Advanced Historical Study (HST401) with Professor Zara Anishanslin. In this research seminar, I wrote a paper based on primary and secondary sources. The topic of my final research paper was how the Patriots influenced the intellect of women during the American Revolution. Once this class had finished, Professor Anishanslin thought that I would be interested in applying for the CSI Undergraduate Research Fellowship. If I got accepted into this fellowship I would become the research assistant for her book, which focuses on a 1765 portrait of a colonial merchant’s wife in a silk dress. Since this sounded like an exciting and interesting project, I applied for the fellowship and was accepted this past June.

As a recipient of the Undergraduate Research Fellowship, I worked alongside Professor Zara Anishanslin as her research assistant for her book, Fashioning Empire. The History Series at Yale University Press will be releasing Fashioning Empire in Fall 2015.
 

Although I am still assisting Professor Anishanslin with her research, I have completed many different tasks thus far. The biggest task that I have completed was coming up with an image log sheet for all of the images that will be used in Fashioning Empire. On this log sheet I included the name of each image, artists names, price quotes for each image, contact information of the institutions that hold the images, .tiff image files, .pdf permission forms, and whether or not permission rights have been granted. The institutions that I have been in touch with regarding gaining the reproduction rights of images include the Winterthur Museum, Victoria and Albert Museum, Library Company of Philadelphia, National Trust, Natural History Museum (London), Museum of Fine Arts (Boston), Rhode Island Historical Society, American Philosophical Society, Newark Museum, Wichita Museum of Art, the de Young Museum, The Huntington Library and Museum, Albany Institute of History and Art, Historical Society of Pennsylvania, Atwater Kent Museum, Philadelphia Landmarks Commission, Rhode Island Historical Society, Harvard Law, Harvard University, and Yale University. In order to gain image permissions from each institution, I had to provide information about the book as well as information about the publication. This image log sheet will be submitted to Yale University Press this fall, before Professor Anishanslin submits the book for publication.

As Professor Anishanslin’s research assistant, I have also fact checked and researched eighteenth-century primary sources, images in museums, online history collections, and other information accessed through different archives. Some of my fact checking was done by ordering off-site primary sources to the New York Public Library and the Butler Library at Columbia University. For example, I ordered microfilms of the Boston Newsletter and Boston Gazette, The Antiquarian magazine, History of the Baptist Church of Oyster Bay, Long Island by Charles S. Wrightman, and Extracts from the Court Books of the Weavers’ Company of London. I mainly used these research materials to confirm information having to do with Robert Feke, Simon Julins, eighteenth-century paintings, and Queen Victoria. In addition to this, I helped locate an 18^th-century probate inventory taken of Charles Apthorp’s estate, located the probate inventory of Thomas Willing, found information on Judah Hayes and Queen Caroline, came to the conclusion that the painting that once hung above the fire mantle at the Rock Hall Museum was a fake copy of Landscape, by Robert Feke, and located the wills of Reverend Ephraim Garthwaite, Reverend Robert Dannye, Thomas Willing, and Anne Willing.

I am so grateful that I was chosen to receive the 2014 Undergraduate Research Award. Gaining image permissions, fact checking, and researching eighteenth-century primary sources has been intellectually rewarding. Not only have I been able to make connections with professionals in my field of interest, but I have also been exposed to many different career options in the field of public history.

Semester Abroad: Bienvenue à Nice, France.

Veronica LaManna, a member of the Verrazano Class of 2016 studying International Business with a minor in French, is spending the Fall 2014 semester in Nice, France.  Veronica arrived in Nice a couple of months ago and is having a great experience so far!  Read below for her first impressions after her arrival in France.

Bienvenue à Nice, France.

I have just begun my study abroad adventure in Nice, France.  I decided to take the same flight as another student who attends the College of Staten Island and who would also be studying at the same school in Nice.  We also decided that it would be better for us to stay with each other and try to find an apartment together.  When we arrived in Nice we did not have an apartment to live in yet, so we stayed in a hostel while we searched for one.  Living in a hostel is something I think everyone should experience.  A hostel is similar to a hotel except it shared with strangers who are usually traveling.  The hostel we stayed in at had two sets of bunk beds, a shower and a sink.  If you needed to use the bathroom, you had to leave the bedroom.  We shared our room with two older women who weren’t from America so they had different ways of doing things that we weren’t used to.  The hostel we stayed at also had rules.  Everyone had to be back in the hostel by 11 o’clock at night.  The hostel also only had Wi-Fi in the lobby downstairs so we weren’t able to have Internet while in the room.  In America we take these small luxuries for granted.  

It was a little hard getting used to life in Europe.  Everything is smaller here, so we had to take turns bringing our luggage up to our room since there was only room for one suitcase in the elevator.  The first few days were extremely stressful since we were jetlagged, unfamiliar with Nice, and living in a different country.  We also were stressed because we wanted to find an apartment to live in quickly. Our school helped us find an apartment, but we had to do most of the work on our own.  It was challenging since we had language barriers with most of the landlords, which caused a few misunderstandings.  After five long days of searching for an apartment we finally found one in Ville Vieux, also known as the Old City.  I have just a ten-minute walk to school and a two-minute walk to the beach.  

The town I live in is very touristy and has a very interesting history.  Our apartment is full of different accents and cultures since it is shared with a few other students who are from different countries.  After getting settled in we had orientation at IPAG, where we got to meet the other Erasmus students and our professors.  In our school we must speak English.  Our student body is made up of students from over thirty different countries.  I have already become friends with so many of the students and it is so interesting to learn about everyone’s culture. Even though the first week was extremely challenging, I have been having an amazing time and I am truly enjoying studying abroad in Nice already.  I am finally getting used to life in Nice and I am looking forward to experiencing this lifestyle for the next four months. 

 

Life Changing Internship At The Brennan Center for Justice

Allison Fremer, a student in the Verrazano Class of 2017, was selected for a competitive internship at the Brennan Center for Justice for Summer 2014.  Here, Allison shares her experience and the opportunities she's had through this internship.

Allison at the Brennan Center for Justice

My name is Allison Fremer, and I’m an Accounting major in the School of Business at the College of Staten Island and a member of the Verrazano Class of 2017.  I am currently a Finance and Operations Intern at the Brennan Center for Justice at New York University Law, where my title is “Junior Accountant.”  I heard about this paid internship opportunity through Joanne Hollan, Associate Director of the Career and Scholarship Center, and Katie Geschwendt, Associate Director of The Verrazano School Honors Program,   Eager to start exploring the workforce, I decided to apply. The application review process was highly competitive. Despite this obstacle, my online resume was one of the top ten finalists.  Then, phone interviews eventually narrowed down the competition to five candidates, including myself. The potential interns were called in for a one-on-one interview at the Brennan Center.  I found out several weeks later that I had landed the internship opportunity.  Believe me, I know it’s a difficult decision choosing between going out with your friends or going to work.  However, I firmly believe that the internship was one of the best decisions I have made. 

The Brennan Center for Justice is located on the Avenue of the Americas in Soho, where there are numerous activities and a large assortment of places to eat.  Through this internship, I’m given a wide variety of tasks including, but certainly not limited to, entering accounts payable invoices, preparing Microsoft Excel spreadsheets in uploadable formats, depositing checks from contributions, maintaining the credit cards for employees, and making adjustments to the budget for the upcoming fiscal year.  The hands-on approach that the Brennan Center has provided me throughout my stay is teaching me in ways that go far beyond what is learned through a textbook.

This internship opportunity has changed my perspective in unimaginable ways and I am excited to continue learning more in the future.  As an intern at the Brennan Center for Justice, I've become more knowledgeable about what is associated with my chosen career path. During the summer, I was offered an extension to my internship, and I made the life-changing decision to continue there during the fall semester.  

Allison with her fellow interns on a break

The professional work environment and being surrounded with positivity has encouraged me to better myself. I have met many intelligent individuals that I will keep in close contact with for a lifetime.  The interns have made a conscious effort to put aside at least one day a week where we eat together to form a bond with one another.  I’ve opened my eyes to cuisines of many cultures that I would have never tried if it wasn’t for my fellow coworkers.

The Brennan Center for Justice has many events including “Brown Bags,” where prominent guest speakers talk. My personal favorite was Andrew Weissmann.  Other events include: “Bagel Tuesdays” where we have a conference with the D.C. office staff members, “Pizza Thursdays”, “Trivia” & “Game Nights”.  The annual barbecue at the home of President Michael Waldman and the annual picnic at McGowan Park in Brooklyn were also among the list of events. 

I’ve learned so much through this internship, and I encourage other Verrazano students to find internships that will help them gain very valuable experience.

Bon Voyage! Verrazano Student Heads To France For Fall Semester

Veronica LaManna, a member of the Verrazano Class of 2016 studying International Business with a minor in French, will be spending the Fall 2014 semester in Nice, France.  Veronica received a Verrazano Study Abroad Scholarship to help support her study abroad endeavor, and she will be sharing her experiences on the Voyager over the coming months.  Read below for her first blog post.

Bonjour! I will be studying in Nice, France during the Fall 2014 semester. Before I came to the College of Staten Island, I knew that my ultimate dream was to travel the world.  Like most college students, choosing a major was very difficult for me.  I knew that I wanted to incorporate my dream of traveling with my area of study. Keeping traveling in mind, I chose to major in business with an international concentration and to minor in French. During my freshman year, a representative from the Center for International Service at the College of Staten Island gave us information about some study abroad programs that were offered.  I knew right away that before I graduated I wanted to study abroad.  Although I was anxious to study abroad, I decided to wait until my junior year of college so I would be able to have more knowledge of the French language.  I also found out that I could potentially receive a scholarship from The Verrazano School that would help with the cost of studying abroad.

I went to the Center for International Service and gathered some more information about studying abroad. I knew that I definitely wanted to study in France because I have taken French classes for seven years and have always loved French culture. The representative from the Center helped me select a program that would fit my field of study and fit my budget.  After a lot of thinking I decided to apply for the CSI Ambassador Exchange Program at IPAG Business School in both Paris and Nice.  This program was perfect for me because it was being offered to only students who are business majors. The students who are accepted pay the College of Staten Island tuition, which is very affordable, along with room and board. Shortly after applying to the program, I received not only an acceptance letter for the program, but also one from the Verrazano School informing me that I had received a scholarship.

I decided to study at the IPAG Business School campus in Nice since I have already been to Paris. Nice is a beautiful city in the Côte d’Azur region located in the South of France. It is the second most popular city to visit in France right after Paris.  The university I will be studying at is only a fifteen-minute walk from the Mediterranean Sea. I will be living in an off campus apartment with another student from the College of Staten Island, and the apartment is located very close to the school. Nice is also situated between Italy and Spain, which are very easy to travel to. IPAG stands for Institut de Préparation à l’Adminstration Générale - that translates into the Institute for General Administration Preparation.  The University is French but most of the student body is made up of Erasmus or exchange students.  My classes will be taught in English, but I will be taking a French class in a level that is not offered at CSI. I will be taking business courses as well, which will give me insight on the economy from another country’s perspective.  I know that university professors in Europe have a very different style of teaching, so I am anxious about being in a different learning environment.  Although I am nervous, this will be a good experience to prepare me for my future career in international business. 

During these final weeks before I leave for France, I am both excited and nervous.  I am excited because this is an opportunity that I have dreamt of for years and it is finally becoming reality.  I am also nervous because I have never been away from my family and friends for so long.  I have also been preparing for my stay by applying for my student visa, looking for a place to stay, and searching for a flight to book.  Through my study abroad experience, I hope to become more proficient in the French language, understand the culture of France and of other countries, learn more about the global economy, and make lasting memories!